who are OUR FIRST patients?

High-risk populations for cancer

Our initial focus is to transform the surveillance of liver cancer in high-risk populations - the fastest growing cause of cancer related deaths.

For example, 10 million people in the United States and Europe are at high risk of developing liver cancer each year, often due to a pre-existing medical condition such as cirrhosis. These patients are enrolled in surveillance programmes for early liver cancer detection, primarily through ultrasound imaging, which is recommended twice yearly due to the fast progression of liver cancer. 

However, detection rates remain low because ultrasound lacks sufficient sensitivity, particularly in overweight individuals. Additionally, poor adherence to the programme is common, as it requires a separate appointment from routine blood tests and is hindered by the known limitations of ultrasound. 

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WHAT DO WE ANALYZE?

Extracellular vesicles (EVs) 
in blood

Extracellular vesicles (EVs) are small, membrane-bound particles continuously released by living cells throughout their lifespan. The cargo of EVs are not exported randomly; they reflect the health status of their parental cells and are enriched with bioactive components involved in critical cellular functions. EVs serve as convenient 'windows' into cellular processes, generally transmitting specific intercellular messages regionally and across organs. 

When a blood sample is taken, it contains billions of these EVs including hundreds of thousands derived from specific organs like the liver. For more visual explanations, please watch our 3D video.

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HOW DO WE ANALYZE?

Pioneering dynamic biopsy

Mursla Bio's transformative biopsy platform is non-invasive and provides a dynamic view of the biological processes within a specific organ or tissue. This approach combines the high accuracy and disease sub-typing precision of tissue biopsies with the simplicity of liquid biopsy sample collection. 

This dynamic biopsy is made possible by leveraging extracellular vesicle (EV) science and an innovative approach called extracellular omics, alongside Mursla Bio’s pioneering technologies. These technologies include: (i) Organ-specific EV isolation, (ii) AI-enabled multi-omics biomarker discovery workflow, and (iii) scalable EV multi-omics assays for clinical use.

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OUR news

Mursla Bio’s EvoLiver surpasses current standards in liver cancer surveillance, data presented at AASLD Liver Meeting 2024

EvoLiver™ demonstrated 86% early-stage sensitivity at 88% specificity for liver cancer surveillance among cirrhotic, high-risk patients with …

Mursla Bio joins leading European consortium to advance clinical applications based on extracellular vesicle science

Mursla Bio was selected to support scaling and commercialization strategy for extracellular vesicle-based disease surveillance and diagnostics …

Mursla Bio enters the US market with strategic expansion

Mursla Bio launches US strategy to bring its novel liquid biopsy tests – based on extracellular vesicle technology – to patients

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