who are OUR FIRST patients?

High-risk populations for cancer

For example, 10 million people in the United States and Europe are at high risk of developing liver cancer each year, often due to a pre-existing medical condition such as cirrhosis. These patients are enrolled in surveillance programmes for early liver cancer detection, primarily through ultrasound imaging, which is recommended twice yearly due to the fast progression of liver cancer. 

However, detection rates remain low because ultrasound lacks sufficient sensitivity, particularly in overweight individuals. Additionally, poor adherence to the programme is common, as it requires a separate appointment from routine blood tests and is hindered by the known limitations of ultrasound. 

A liquid biopsy test could address these challenges.

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WHAT DO WE ANALYSE?

Extracellular vesicles (EVs) 
in blood

Healthy, abnormal and cancerous cells secrete thousands of tiny membrane-bound vesicles per day known as Extracellular Vesicles (EVs). EVs carry multi-omics cargo such as DNA, RNA, proteins, lipids, and metabolites. When a blood sample is taken, it contains billions of these EVs including hundreds of thousands derived from specific organs like the liver. For more visual explanations, please watch our 3D video.

Once considered mere cellular waste, EVs are now recognised for their crucial role in facilitating communication between cells and organs across both short and long distances. They have been recently shown to play a significant part in both health and diseases, including cancer.

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HOW DO WE ANALYSE?

Pioneering EV liquid biopsy platform

Mursla Bio's cutting-edge technologies analyse the cargo of organ-specific EVs in blood, such as those originating from the liver, with unmatched precision. This enables advanced, non-invasive tissue biopsies of patients at any time, detecting diseases like cancer at their earliest stages.

Mursla Bio pioneered three EV technologies to achieve optimal clinical outcomes: (i) Organ-specific EV isolation, (ii) AI-enabled multi-omics biomarker discovery from EV cargo, (iii) Scalable EV multi-omics assays for clinical use.


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OUR news

Mursla Bio enters the US market with strategic expansion

Mursla Bio launches US strategy to bring its novel liquid biopsy tests – based on extracellular vesicle technology – to patients
NEXOS

Mursla Bio presents breakthrough liquid biopsy technology for extracellular vesicles in Cell Press

Novel and scalable analysis of extracellular vesicles sub-types detailed in Cell Press’ iScience

Mursla Bio helps shape the standardisation of EV-based liquid biopsy for clinical use

Mursla Bio participates in a unique global initiative to standardise the clinical use of novel EV-based biomarkers for liquid biopsy

Our Partners